Value Score93/100Best Value
CoreAge Rx
#1 · Grade A+ · Best Value
Est. first month
$99/mo
No teaser step-up. The honest lowest price: both molecules at one flat, all-in monthly rate that never steps up after month one.
Cheaper & better value
Alternatives to Piper
Piper scores a 84 on our Value Score. These are the top-ranked GLP-1 deals we'd point you to instead — every one scored on the same six factors, with the teaser-rate traps flagged so you pay the honest lower price.
Save ~89%
Value Score87/100Great Deal
NewSelf
#13 · Grade A- · Great Deal
Est. first month
$134.99/mo at every dose (as low as $99.97 on a longer plan)
No teaser step-up. NewSelf sells compounded semaglutide with B12 or glycine at $134.99 a month and compounded tirzepatide with B6 and glycine at $224.99, both held flat across every dose, in 49 states.
FDA warning letter. The FDA issued NewSelf Limited dba NewSelf a warning letter in February 2026. Check it on the FDA database.
Value Score84/100Good Value
NextMeds
#30 · Grade B+ · Good Value
Est. first month
From $129/mo (plus a separate fee, compounded)
Pricing to watch. NextMeds is a cash-pay telehealth platform offering compounded semaglutide and compounded tirzepatide on a flat monthly membership — one price bundling the medication.
Value Score84/100Good Value
Big Easy Weight Loss
#25 · Grade B+ · Good Value
Est. first month
$145/mo equivalent on a $399 12-week new-patient starter ($179/mo after)
Pricing to watch. Big Easy Weight Loss is a New Orleans doctor-run telehealth service selling compounded GLP-1s in 12-week blocks - $399 for semaglutide and $499 for tirzepatide as a new-patient starter, $495 and $599 after.
Value Score80/100Good Value
Precision Telemed
#65 · Grade B · Good Value
Est. first month
From $139.99/mo
Pricing to watch. A multi-vertical telehealth storefront where the GLP-1s are priced from $139.99, and where the cheapest number on the front page belongs to a peptide rather than to either weight-loss drug.
Value Score86/100Great Deal
Ondra Health
#17 · Grade A- · Great Deal
Est. first month
$149/mo
Pricing to watch. Semaglutide at $149 a month with no membership fee and one price at every dose, as long as you read past the $96 on the front page - that number is a year paid up front.
Value Score79/100Fair Price
Blis MD
#70 · Grade B · Fair Price
Est. first month
$139/mo
No teaser step-up. Blis MD is a US telehealth offering personalized GLP-1 weight-loss treatment with compounded semaglutide and tirzepatide, prescribed after a free virtual consultation with a licensed provider.
Value Score79/100Fair Price
AgelessRx
#82 · Grade B · Fair Price
Est. first month
From $139/mo (four-month plan; no month-to-month rate published)
Pricing to watch. A longevity clinic that sells GLP-1s alongside NAD+ and low-dose naltrexone, with a $139 headline that belongs to its four-month plan rather than to any month you could actually buy on its own.
Value Score80/100Good Value
KERNX Health
#60 · Grade B · Good Value
Est. first month
From $129/mo (compounded, plus a one-time consultation fee)
No teaser step-up. One of the few compounded sellers that publishes what every dose costs, so the entry price can be checked against the dose you would actually be prescribed.
Ranked by our Value Score — our editorial judgment per the methodology. “Save” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Assume any provider we list may compensate us — it never changes a Value Score. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.