Head-to-head · Value Score
Trimi Health vs Sesame Care
Two GLP-1 deals, scored on the same six factors. Trimi Health lands a Value Score of 89, Sesame Care a 87. Here's who gives you the honest lower price — and where each one bites back.
Trimi Health
#2 · Grade A · Great Deal
Est. first month
$99/mo on the annual plan
Save ~93% vs brand-nameSesame Care
#5 · Grade A- · Great Deal
Est. first month
$149/mo for the drug alone, plus Sesame's membership ($99 billed every 28 days, or $59/mo only on the 12-month prepay)
Save ~89% vs brand-nameThe verdict
Trimi Health takes it on Value Score, 89 to 87 — an est. $99/mo on the annual plan first month, though we flag its pricing to watch. Sesame Care isn't out of it: Shoppers who want genuine FDA-approved brand-name GLP-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program.
Deal-by-deal
The numbers that decide it. Green ✓ marks the stronger side on each line.
| Deal | Trimi Health | Sesame Care |
|---|---|---|
| Value Score | 89 (A) | 87 (A-) |
| Est. first month | $99/mo on the annual plan | $149/mo for the drug alone, plus Sesame's membership ($99 billed every 28 days, or $59/mo only on the 12-month prepay) |
| Save vs brand-name | ~93% | ~89% |
| Semaglutide | $99/mo on the annual plan | Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) |
| Tirzepatide | $125/mo on the annual plan | Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days |
| Both molecules | Yes | Yes |
| Pricing | Watch | Watch |
| Coverage | All 50 states | Nationwide marketplace |
Factor by factor
The six factors behind each Value Score. The orange bar marks the stronger side. See the methodology.
Trimi Health
Two of the lowest per-month figures in the ranking, held flat at every dose and unusually open about who fills them — but both are annual-plan rates, and no month-to-month price is published at all.
Why it's a deal
- Two of the lowest per-month figures we track, on the annual plan — $99 semaglutide and a class-low $125 tirzepatide
- The price is flat at every dose, so a titration up does not cost more. That is the part of the "flat" claim that holds
- Names its compounding pharmacies — VialsRx, with its Texas Board of Pharmacy number published, and GreenwichRx — and names Arora Health as the clinician network. Most sellers at this price name nobody
- One membership covers the medication, clinician visits, ongoing check-ins and shipping, with 24/7 provider messaging and no separate fees advertised
- Nationwide 50-state reach, so the low price is not gated to a handful of states, and it is FSA and HSA eligible
The fine print
- $99 and $125 are annual-plan prices. Trimi publishes no month-to-month rate anywhere, so the real question — what one month costs if you stop — is one you have to ask before you sign up
- Because the term is a year, the comparison against a flat month-to-month rival is not like for like, however good the number looks
- No cancellation terms or notice period are published, which matters more on a year-long plan than a monthly one
- Not LegitScript-certified — worth your own diligence before buying on price alone
- Compounded injectable only — no FDA-approved brand-name or oral route, and compounded medication is not itself FDA-approved
- Newer brand with a thin public track record
Sesame Care
An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
Why it's a deal
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
- Oral routes available (Wegovy pill, Rybelsus)
The fine print
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Value Score.
Neither one the right fit? Every program that outscores Trimi Health is ranked on the Trimi Health alternatives ranking, and the same list for the other side is on alternatives to Sesame Care.
More head-to-heads
Prices, states and verification reflect each program's public disclosures at last check; the Value Score is our editorial judgment per the methodology. “Save vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.