Head-to-head · Value Score
RxSpan MD vs ShedRx
Two GLP-1 deals, scored on the same six factors. RxSpan MD lands a Value Score of 86, ShedRx a 84. Here's who gives you the honest lower price — and where each one bites back.
RxSpan MD
#12 · Grade A- · Great Deal
Est. first month
$194/mo
Save ~86% vs brand-nameShedRx
#23 · Grade B+ · Good Value
Est. first month
$199/mo
Save ~85% vs brand-nameThe verdict
RxSpan MD takes it on Value Score, 86 to 84 — an est. $194/mo first month, though we flag its pricing to watch. ShedRx isn't out of it: Shoppers happy to commit to twelve months for the lowest rate, or who want a lower-cost oral route.
Deal-by-deal
The numbers that decide it. Green ✓ marks the stronger side on each line.
| Deal | RxSpan MD | ShedRx |
|---|---|---|
| Value Score | 86 (A-) | 84 (B+) |
| Est. first month | $194/mo | $199/mo |
| Save vs brand-name | ~86% | ~85% |
| Semaglutide | From $194/mo | $199/mo |
| Tirzepatide | $329/mo | $299/mo |
| Both molecules | Yes | Yes |
| Pricing | Watch | Watch |
| Coverage | All 50 states | All 50 states |
Factor by factor
The six factors behind each Value Score. The orange bar marks the stronger side. See the methodology.
RxSpan MD
A broad, physician-led menu — compounded and oral GLP-1 plus an advertised brand-name lane under a named plastic surgeon — with transparent, all-inclusive pricing from ~$194/mo (annual) across all 50 states.
Why it's a deal
- Available in all 50 states
- Transparent, all-inclusive published pricing — consult, medication, supplies, shipping, and support in one price; cancel or change plans anytime, with a low annual entry from ~$194/mo on compounded semaglutide
- Both injectable and a real oral (capsule) route, on compounded sema/tirz plus an advertised brand-name lane
- Physician-led by a named, board-certified founder (Dr. John Diaz, plastic surgeon); 24/7 unlimited messaging and coaching, free shipping
The fine print
- Compounded semaglutide/tirzepatide are not FDA-approved — not the same as Wegovy, Ozempic, or Zepbound
- Published pricing shown is for the compounded line — brand-name pricing isn't itemized
- Prescription isn't guaranteed — a provider reviews eligibility after checkout
ShedRx
Good headline prices and four routes to a GLP-1 — but the cheapest numbers it advertises need a year-long commitment.
Why it's a deal
- Four routes — injection, liquid drops, lozenges and a daily oral pill — plus brand Zepbound and Wegovy
- $299 month-to-month tirzepatide is still competitive against flat-fee rivals
- Available in all 50 states, with health coaching included
The fine print
- The advertised "as low as $239" needs a twelve-month commitment — month-to-month is $299
- Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
- The dispensing compounding pharmacy is not publicly named
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Value Score.
Neither one the right fit? Every program that outscores RxSpan MD is ranked on the RxSpan MD alternatives ranking, and the same list for the other side is on alternatives to ShedRx.
More head-to-heads
Prices, states and verification reflect each program's public disclosures at last check; the Value Score is our editorial judgment per the methodology. “Save vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.