RxSpan MD review
Value Score86/100
A broad, physician-led menu - compounded and oral GLP-1 plus an advertised brand-name lane under a named plastic surgeon - priced at $249 a month for semaglutide, with the advertised low rates attached to a plan.
We earn a commission when you start treatment through some links on this site, at no extra cost to you. CoreAge Rx is a featured partner, and providers we work with may appear first. It never changes the Value Score.
Advertised price
From $249/mo
$249/mo month-to-month (as low as $175/mo on the 12-month plan)
How much does RxSpan MD cost?
The price RxSpan MD publishes is $249/mo month-to-month (as low as $175/mo on the 12-month plan). Tirzepatide is listed at $329/mo month-to-month (as low as $243/mo). We flag this one to watch: confirm the ongoing rate with RxSpan MD before you count on it.
- Semaglutide
- $249/mo month-to-month (as low as $175/mo on the 12-month plan)
- Tirzepatide
- $329/mo month-to-month (as low as $243/mo)
- Coverage
- All 50 states
- Brand-name
- Yes
The Value Score card
RxSpan MD scored on our six published factors. See the methodology.
RxSpan MD · 86/100
From $249/mo
What's good
- Available in all 50 states
- Transparent, all-inclusive published pricing — consult, medication, supplies, shipping and support in one price; cancel or change plans anytime, with the card advertising as low as $175/mo on compounded semaglutide for anyone who commits to a plan
- Both injectable and a real oral (capsule) route, on compounded sema/tirz plus an advertised brand-name lane
- Physician-led by a named, board-certified founder (Dr. John Diaz, plastic surgeon); 24/7 unlimited messaging and coaching, free shipping
Read the fine print
- Compounded semaglutide and tirzepatide are not FDA-approved and are not the same as Wegovy, Ozempic or Zepbound
- RxSpan MD's brand-name lane is expensive: $1,069 for a first month of Zepbound, $1,299 for Ozempic and $1,349 for Wegovy
- RxSpan MD's $175 and $243 rates need a 12-month plan paid up front with a promo code, and that plan auto-renews
- Prescription isn't guaranteed at RxSpan MD — a provider reviews eligibility after checkout
The bottom line
Best for: People who want a wide, doctor-fronted menu with all-inclusive pricing and nationwide coverage, and who will budget against the month-to-month figure rather than the advertised one.
For comparison, see CoreAge Rx, a featured partner (Value Score 81/100).
Programs to compare
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- VisitTrimi HealthPartner
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Compare with other deals
The programs scoring closest to RxSpan MD, out of 428 others we track.
Shopping RxSpan MD against a specific rival? We put it head to head with our featured partner on CoreAge Rx vs RxSpan MD, and every program that undercuts or outscores it — starting with Eden, the closest match on score — is ranked on the RxSpan MD alternatives ranking.
- $99/moEden— Eden’s current compounded injection plans advertise $99 monthly semaglutide and $129 tirzepatide including care, but its older offers and warranty terms still need clarification before you pay.91/100
- $134.99/mo at every doseNewSelf— NewSelf sells compounded semaglutide with B12 or glycine at $134.99 a month and compounded tirzepatide with B6 and glycine at $224.99, both held flat across every dose, in 49 states.87/100
- From $99/moFresh Day Meds— Weekly compounded injections from $99 for semaglutide and $140 for tirzepatide, sold beside four other treatment categories - the prices are visible up front, but they are floors rather than fixed rates.86/100
- From $99/moStrut Health— Strut offers semaglutide injections at $129 a month and tirzepatide injections from $149 on auto-refill. Its needle-free options broaden the menu, but conflicting semaglutide lozenge prices need confirmation before purchase.85/100
- From $79/moEmbody— Embody offers compounded semaglutide and tirzepatide via injection plus a unique compounded oral tirzepatide gum formulation.85/100
- From $99/moJyra Health— Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers.85/100
More programs we track (24)
- Vitara RX85
- Ondra Health85
- Gimme Care85
- Mint Med85
- Elara Health and Wellness85
- Sunlight85
- No BS RX85
- Trimi Health84
- HealthRX84
- Sprout Health84
- yourEra84
- Big Easy Weight Loss84
- CoraDoc84
- Effecty84
- Kongo84
- MyFastRx84
- NextMeds84
- REMEVi84
- ZYP Medical84
- bmiMD83
- MadeMed83
- Candor Rx83
- Cora Health83
- Polly83
395 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page come from RxSpan MD's own website; the Value Score is our editorial judgment per the methodology."% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on RxSpan MD's site. Not medical advice; see our disclosure.