What is the best semaglutide program?

Of the 394 programs that publish a real semaglutide price, Eden ranks highest on our Value Score at 91/100 — Eden’s current compounded injection plans advertise $99 monthly semaglutide and $129 tirzepatide including care, but its older offers and warranty terms still need clarification before you pay. That is a different answer than "cheapest": the lowest sticker among the same set is WellMedr at Not published as a monthly price — a "Starting At $49" fall-sale floor on a plan billed every 21 days.

What does "best" mean here if it isn't the cheapest price?

Our Value Score weighs price alongside five other factors — coverage, cancellation terms, whether the rate holds after month one, and more. A program can publish a low first-month number and still score lower here if that number doesn't hold, or if it comes with restrictions a cheaper-looking ranking wouldn't show you.

How much cheaper is compounded semaglutide than brand-name Wegovy?

Against Wegovy's October 2026 self-pay price of $349/mo, the top-ranked flat price here runs meaningfully lower — see the per-row percentage below. Compounded semaglutide is a different, non-FDA-approved product, not a generic of Wegovy, which is why we always show this as a comparison, never an equivalence.

Is this the same list as the cheapest semaglutide ranking?

Overlapping but reordered. Both draw from the same 394 programs with a disclosed semaglutide price. The cheapest ranking sorts strictly ascending by that price; this one sorts by Value Score, so a program with a higher sticker but a flat rate and full state coverage can rank above a cheaper one flagged "watch."

Updated October 2026

Compounded semaglutide online: prices compared

394 online programs publish a compounded semaglutide price. Ranked by our Value Score, with every price shown.

The short answer

Among 16 plain monthly semaglutide offers, the median is $179. The lowest price that holds in month two is $99/mo, at Eden.

$179

Monthly-only median

$99

Lowest flat price

394

Programs compared

Check price at Eden Read the review

Which online programs sell compounded semaglutide, and for how much?

The 8 highest Value Scores at a glance. For the lowest prices first, see the cheapest semaglutide price ladder.

Compounded semaglutide programs with the highest Value Scores
Program	Semaglutide	Month two	Coverage
EdenPartner	$99/mo	✓ Same price	All 50 states
NewSelf	From $134/mo	✓ Same price	49 states
Fresh Day Meds	From $99/mo	! Confirm first	All 50 states
RxSpan MDPartner	From $249/mo	! Confirm first	All 50 states
Elara Health and Wellness	From $183/mo	! Confirm first	All 50 states
Embody	From $79/mo	! Confirm first	All 50 states
Gimme Care	From $160/mo	! Confirm first	All 50 states
Jyra Health	From $99/mo	! Confirm first	All 50 states

What changed in October 2026

New: RNK Health, EverPrime are now on our list.
Gone: Nalena, AMP Health, PeptidesRx no longer sell GLP-1s, so they are off every price list.
Re-checked: 52 programs had their price read again on their own site.

Every compounded semaglutide program, by Value Score

Value-Score sorted, not price-sorted

50 of 394 charge the same in month two. Assume any program we list may compensate us; it never moves this order. See our disclosure.

01
EdenPartner
$99/moHolds flat~72% under brand self-payScore 91
Check price
02
NewSelf
From $134/moHolds flatScore 87
Check price
$134.99/mo at every dose (as low as $99.97 on a longer plan)
03
Fresh Day Meds
From $99/moConfirm month 2Score 86
Check price
04
RxSpan MDPartner
From $249/moConfirm month 2Score 86
Check price
$249/mo month-to-month (as low as $175/mo on the 12-month plan)
05
Elara Health and Wellness
From $183/moConfirm month 2Score 85
Check price
$183/mo on the annual plan ($2,196 billed annually)
06
Embody
From $79/moConfirm month 2Score 85
Check price
From $79/mo (all doses, promotional rate, compounded)
07
Gimme Care
From $160/moConfirm month 2Score 85
Check price
$160/mo month-to-month ($130/mo on a 3-month plan)
08
Jyra Health
From $99/moConfirm month 2Score 85
Check price
From $99/mo (starting dose, plus a separate fee, compounded)
09
Mint Med
From $106/moHolds flatScore 85
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$106/mo (all doses)
10
No BS RX
From $179/moHolds flatScore 85
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$179/mo month-to-month (a separate low-dose program is $140)
11
Ondra Health
$149/moConfirm month 2~57% under brand self-payScore 85
Check price
12
Strut HealthPartner
From $129/moConfirm month 2Score 85
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$129/mo injectable on auto-refill · oral lozenge as low as $99/mo on auto-refill (Strut's semaglutide overview lists the lozenge at $199 for a 30-day supply)
13
Sunlight
From $88/moHolds flatScore 85
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$88/mo (flat, injection only — no step-up)
14
Vitara RX
From $99/moConfirm month 2Score 85
Check price
From $99/mo (compounded injection; confirm total at checkout)
15
Big Easy Weight Loss
From $145/moConfirm month 2Score 84
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$145/mo equivalent on a $399 12-week new-patient starter ($179/mo after)
16
CoraDoc
From $99/moConfirm month 2Score 84
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From $99/mo (all doses, compounded)
17
Effecty
From $160/moConfirm month 2Score 84
Check price
From $160/mo (compounded)
18
HealthRXPartner
From $165/moConfirm month 2Score 84
Check price
$165/mo month-to-month on Subscribe & Save after a $149 first month ($190 for a single month) · $125/mo on a 3-month plan ($374 every 3 months) · $97/mo on a 12-month plan ($1,163 up front)
19
Kongo
From $119/moHolds flatScore 84
Check price
From $119/mo (all doses, plus a separate fee, compounded)
20
MyFastRx
$169/moHolds flat~52% under brand self-payScore 84
Check price

That is the top 20 of 394 priced semaglutide programs. Every one of the other 374 still has its own review and ranks somewhere on the full index.

Is the best compounded semaglutide program the cheapest one?

Eden has the highest Value Score on this list, 91/100, publishing semaglutide at $99/mo. The lowest sticker among the same 394 programs belongs to WellMedr at Not published as a monthly price — a "Starting At $49" fall-sale floor on a plan billed every 21 days, a price with terms to confirm before you count on it.

Neither number is wrong; they answer different questions. If price is the only thing you're optimizing, start with the cheapest semaglutide ladder and read the teaser flag on whatever comes up first. If you want the program most likely to be a good deal on the whole — the rate that still looks good in month six — this site is built for that instead.

Brand-name Wegovy and Ozempic are Novo Nordisk's FDA-approved semaglutide; most programs above sell compounded semaglutide, a different, non-FDA-approved product. Vet the pharmacy before you shop on either axis — start with is cheap compounded GLP-1 safe?.

Which ranking is for you

Cheapest semaglutide, ranked by price — the same eligible set, sorted strictly ascending by sticker price.
Compounded semaglutide online: prices compared — this page: quality-first, price is one factor of six.
Best tirzepatide, ranked by Value Score — the same approach for the other molecule.
Cheapest GLP-1 programs, ranked — every program regardless of molecule, cheapest sticker first.

Compounded semaglutide online: common questions

What is the best semaglutide program?: Of the 394 programs that publish a real semaglutide price, Eden ranks highest on our Value Score at 91/100 — Eden’s current compounded injection plans advertise $99 monthly semaglutide and $129 tirzepatide including care, but its older offers and warranty terms still need clarification before you pay. That is a different answer than "cheapest": the lowest sticker among the same set is WellMedr at Not published as a monthly price — a "Starting At $49" fall-sale floor on a plan billed every 21 days.
What does "best" mean here if it isn't the cheapest price?: Our Value Score weighs price alongside five other factors — coverage, cancellation terms, whether the rate holds after month one, and more. A program can publish a low first-month number and still score lower here if that number doesn't hold, or if it comes with restrictions a cheaper-looking ranking wouldn't show you.
How much cheaper is compounded semaglutide than brand-name Wegovy?: Against Wegovy's October 2026 self-pay price of $349/mo, the top-ranked flat price here runs meaningfully lower — see the per-row percentage below. Compounded semaglutide is a different, non-FDA-approved product, not a generic of Wegovy, which is why we always show this as a comparison, never an equivalence.
Is this the same list as the cheapest semaglutide ranking?: Overlapping but reordered. Both draw from the same 394 programs with a disclosed semaglutide price. The cheapest ranking sorts strictly ascending by that price; this one sorts by Value Score, so a program with a higher sticker but a flat rate and full state coverage can rank above a cheaper one flagged "watch."

Next: semaglutide vs tirzepatide: the cheaper effective GLP-1, or compare any two programs head-to-head.

Not medical advice; see our medical disclaimer and methodology.