Head-to-head · Value Score
Trimi Health vs SkyRx
Two GLP-1 deals, scored on the same six factors. Trimi Health lands a Value Score of 89, SkyRx a 63. Here's who gives you the honest lower price — and where each one bites back.
Trimi Health
#3 · Grade A · Great Deal
Est. first month
$99/mo
Save ~93% vs brand-nameSkyRx
#340 · Grade C · Watch List
Est. first month
From $199/mo (all doses, compounded)
Save ~85% vs brand-nameThe verdict
Trimi Health takes it on Value Score, 89 to 63 — an est. $99/mo first month, with no teaser step-up baked in. SkyRx isn't out of it: Shoppers wanting all-inclusive compounded semaglutide with supplies included.
Deal-by-deal
The numbers that decide it. Green ✓ marks the stronger side on each line.
| Deal | Trimi Health | SkyRx |
|---|---|---|
| Value Score | 89 (A) | 63 (C) |
| Est. first month | $99/mo | From $199/mo (all doses, compounded) |
| Save vs brand-name | ~93% | ~85% |
| Semaglutide | $99/mo | From $199/mo (all doses, compounded) |
| Tirzepatide | $125/mo | Not disclosed |
| Both molecules | Yes | No |
| Pricing | Flat — no step-up | Watch |
| Coverage | All 50 states | Coverage not published |
Factor by factor
The six factors behind each Value Score. The orange bar marks the stronger side. See the methodology.
Trimi Health
The ultra-budget pick: two-digit semaglutide and a $125 tirzepatide — one of the lowest flat tirz stickers on the whole board — shipped to all 50 states.
Why it's a deal
- Ultra-budget on both molecules — $99 semaglutide and a class-low $125 tirzepatide, flat with no teaser step-up
- Tirzepatide at $125/mo undercuts most of the flat-fee field on the priciest molecule
- Nationwide 50-state reach, so the low price isn't gated to a handful of states
The fine print
- Not LegitScript-certified — do your own pharmacy diligence before you buy on price alone
- Compounded injectable only — no FDA-approved brand-name or oral/sublingual route
- Newer brand with a thin public track record
SkyRx
SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.
Why it's a deal
- All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
- Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
- Same-day shipping for orders before 2pm ET in temperature-controlled packaging
The fine print
- 199 dollars pricing requires a 12-month subscription paid upfront
- Tirzepatide only listed as coming soon
- GLP-1s not yet available in all 50 states; specific states not listed
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Value Score.
Neither one the right fit? Every program that outscores Trimi Health is ranked on the Trimi Health alternatives board, and the same list for the other side is on alternatives to SkyRx.
More head-to-heads
Prices, states and verification reflect each program's public disclosures at last check; the Value Score is our editorial judgment per the methodology. “Save vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.