SkyRx review
Value Score63/100
SkyRx sells compounded semaglutide as either an injection or oral drops from $199 a month on a twelve-month prepaid plan, dispensed through FDA-registered 503B pharmacies, with tirzepatide still listed as coming soon.
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Advertised price
From $199/mo
From $199/mo (all doses, 12-month plan, compounded)
How much does SkyRx cost?
The price SkyRx publishes is From $199/mo (all doses, 12-month plan, compounded). We flag this one to watch: confirm the ongoing rate with SkyRx before you count on it.
- Semaglutide
- From $199/mo (all doses, 12-month plan, compounded)
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
The Value Score card
SkyRx scored on our six published factors. See the methodology.
What's good
- Dispenses through US-based 503B compounding pharmacies registered with the FDA — the more heavily regulated of the two routes, and stated explicitly
- Maintains LegitScript certification
- Oral drops are priced the same as the injection at $199, so the needle-free route carries no premium
- Says outright that GLP-1s are not available in every state rather than implying nationwide coverage
Read the fine print
- The $199 rate requires a twelve-month subscription paid up front — there is no month-to-month figure published beside it
- Tirzepatide is listed as coming soon in both injection and oral form, so semaglutide is the only real choice today
- The states it does serve are never enumerated, so eligibility is unknown until you apply
- Compounded only — no FDA-approved brand-name route
The bottom line
Best for: Someone committed to semaglutide for a year who wants a 503B pharmacy behind it.
For comparison, see CoreAge Rx, a featured partner (Value Score 81/100).
Programs to compare
Compare with other deals
The programs scoring closest to SkyRx, out of 428 others we track.
Shopping SkyRx against a specific rival? We put it head to head with our featured partner on CoreAge Rx vs SkyRx, and every program that undercuts or outscores it — starting with Nurx, the closest match on score — is ranked on the SkyRx alternatives ranking.
- From $179/moNurx— Nurx is an established telehealth brand, best known for birth control, that also runs a weight-management program billed monthly or quarterly and works with insurance where a plan will cover it.63/100
- From $299/moPrideRx— PrideRx is an LGBTQ+-friendly telehealth platform offering brand-name-only GLP-1 weight loss — Zepbound (tirzepatide) from $299/mo, Wegovy Pill (oral semaglutide) from $149/mo, and Foundayo (orforglipron).63/100
- From $249/moRemi Meds— Remi Meds is a DTC compounded-GLP-1 telehealth platform offering per-dose-tier compounded semaglutide and tirzepatide-with-B12, plus NAD+, Sermorelin, and Glutathione add-ons.63/100
- From $198/moTeleZen MD— TeleZen MD is a fully online US telehealth service covering all 50 states, dispensing compounded GLP-1s through 503A and 503B pharmacies with free expedited delivery and 24/7 support.63/100
- $399/moWeightCare— WeightCare is a compounded-GLP-1 subscription that takes payment for the first month before the health questionnaire, then has a board-certified physician review it, with renewals at $499 a month or cheaper multi-month blocks.63/100
- $269/mo month-to-month on the four-week planSexyMD— Compounded semaglutide at $269 a month and tirzepatide at $369, headlined everywhere on the site as $199 and $299 — the rates for committing to forty-eight weeks.63/100
More programs we track (24)
- Roboclinic64
- RxSaludable64
- Whoosh Wellness64
- MyDrHank63
- Elara MD63
- Eve63
- Fierce Health63
- Freya Meds63
- Livea63
- Medivive63
- Noom Med63
- Novi63
- Prime Doctor RX63
- HumeCare+62
- SnagRx62
- Willow62
- EverPrime62
- Actin62
- Aspen62
- Dr. Arevitalize62
- Florida Weight Loss MD62
- iThriveMD62
- Levity62
- Next Vial62
395 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page come from SkyRx's own website; the Value Score is our editorial judgment per the methodology."% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on SkyRx's site. Not medical advice; see our disclosure.