SkyRx review
SkyRx sells compounded semaglutide as either an injection or oral drops from $199 a month on a twelve-month prepaid plan, dispensed through FDA-registered 503B pharmacies, with tirzepatide still listed as coming soon.
Est. first month
From $199/mo
From $199/mo (all doses, 12-month plan, compounded)
How much does SkyRx cost?
The price SkyRx publishes is From $199/mo (all doses, 12-month plan, compounded). We flag this one to watch: confirm the ongoing rate with SkyRx before you count on it, because a low first month can step up afterward. That works out about 85% under our ~$1,349/mo brand-name cash reference.
- Semaglutide
- From $199/mo (all doses, 12-month plan, compounded)
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
The Value Score card
SkyRx scored on our six published factors. See the methodology.
Why it's a deal
- Dispenses through US-based 503B compounding pharmacies registered with the FDA — the more heavily regulated of the two routes, and stated explicitly
- Maintains LegitScript certification
- Oral drops are priced the same as the injection at $199, so the needle-free route carries no premium
- Says outright that GLP-1s are not available in every state rather than implying nationwide coverage
Read the fine print
- The $199 rate requires a twelve-month subscription paid up front — there is no month-to-month figure published beside it
- Tirzepatide is listed as coming soon in both injection and oral form, so semaglutide is the only real choice today
- The states it does serve are never enumerated, so eligibility is unknown until you apply
- Compounded only — no FDA-approved brand-name route
The bottom line
Best for: Someone committed to semaglutide for a year who wants a 503B pharmacy behind it. SkyRx sells compounded semaglutide as either an injection or oral drops from $199 a month on a twelve-month prepaid plan, dispensed through FDA-registered 503B pharmacies, with tirzepatide still listed as coming soon.
Ranked #350 of 427 programs we track — see our #1 deal, CoreAge Rx, for comparison.
Compare with other deals
The programs scoring closest to SkyRx, out of 426 others we track.
Shopping SkyRx against a specific rival? We put it head to head with our top-scoring pick on CoreAge Rx vs SkyRx, and every program that undercuts or outscores it — starting with Nurx, the closest match on score — is ranked on the SkyRx alternatives ranking.
- From $179/mo (starting dose, compounded)Nurx— Nurx is an established telehealth brand, best known for birth control, that also runs a weight-management program billed monthly or quarterly and works with insurance where a plan will cover it.63/100
- From $299/mo (2.5 mg dose, plus a separate fee, brand-name)PrideRx— PrideRx is an LGBTQ+-friendly telehealth platform offering brand-name-only GLP-1 weight loss — Zepbound (tirzepatide) from $299/mo, Wegovy Pill (oral semaglutide) from $149/mo, and Foundayo (orforglipron).63/100
- From $249/mo (0.25 mg dose, compounded)Remi Meds— Remi Meds is a DTC compounded-GLP-1 telehealth platform offering per-dose-tier compounded semaglutide and tirzepatide-with-B12, plus NAD+, Sermorelin, and Glutathione add-ons.63/100
- From $198/mo (compounded)TeleZen MD— TeleZen MD is a fully online US telehealth service covering all 50 states, dispensing compounded GLP-1s through 503A and 503B pharmacies with free expedited delivery and 24/7 support.63/100
- $219/moTRT Nation— TRT Nation is a men's telehealth platform focused primarily on testosterone replacement therapy, with compounded GLP-1 weight loss as a secondary vertical.63/100
- $399/moWeightCare— WeightCare is a compounded-GLP-1 subscription that takes payment for the first month before the health questionnaire, then has a board-certified physician review it, with renewals at $499 a month or cheaper multi-month blocks.63/100
More programs we track (24)
- #335 RxSaludable64
- #336 TeleHealth Weight Solutions64
- #337 Whoosh Wellness64
- #314 MyDrHank63
- #339 Elara MD63
- #340 Eve63
- #341 Fierce Health63
- #342 Freya Meds63
- #343 Livea63
- #344 Medivive63
- #345 Noom Med63
- #346 Novi63
- #354 SexyMD63
- #355 Prime Doctor RX63
- #325 SnagRx62
- #357 Actin62
- #358 Aspen62
- #359 Dr. Arevitalize62
- #360 Florida Weight Loss MD62
- #361 iThriveMD62
- #362 Levity62
- #363 Next Vial62
- #364 PrescribedRX62
- #365 Tonik Wellness62
396 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page were read from SkyRx's own website on ; the Value Score is our editorial judgment per the methodology. “% vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on SkyRx's site. Not medical advice; see our disclosure.