Head-to-head · Value Score
RxSpan MD vs Vaylen
Two GLP-1 deals, scored on the same six factors. RxSpan MD lands a Value Score of 86, Vaylen a 87. Here's who gives you the honest lower price — and where each one bites back.
RxSpan MD
#12 · Grade A- · Great Deal
Est. first month
$194/mo
Save ~86% vs brand-nameVaylen
#21 · Grade A- · Great Deal
Est. first month
$179/mo
Save ~87% vs brand-nameThe verdict
Vaylen takes it on Value Score, 87 to 86 — an est. $179/mo first month, with no teaser step-up baked in. RxSpan MD isn't out of it: Shoppers who want a wide, doctor-fronted menu with upfront, all-inclusive pricing and nationwide coverage, and who don't mind that the lowest rate takes an annual commitment.
Deal-by-deal
The numbers that decide it. Green ✓ marks the stronger side on each line.
| Deal | RxSpan MD | Vaylen |
|---|---|---|
| Value Score | 86 (A-) | 87 (A-) |
| Est. first month | $194/mo | $179/mo |
| Save vs brand-name | ~86% | ~87% |
| Semaglutide | From $194/mo | $179/mo |
| Tirzepatide | $329/mo | $239/mo |
| Both molecules | Yes | Yes |
| Pricing | Watch | Flat — no step-up |
| Coverage | All 50 states | All 50 states |
Factor by factor
The six factors behind each Value Score. The orange bar marks the stronger side. See the methodology.
RxSpan MD
A broad, physician-led menu — compounded and oral GLP-1 plus an advertised brand-name lane under a named plastic surgeon — with transparent, all-inclusive pricing from ~$194/mo (annual) across all 50 states.
Why it's a deal
- Available in all 50 states
- Transparent, all-inclusive published pricing — consult, medication, supplies, shipping, and support in one price; cancel or change plans anytime, with a low annual entry from ~$194/mo on compounded semaglutide
- Both injectable and a real oral (capsule) route, on compounded sema/tirz plus an advertised brand-name lane
- Physician-led by a named, board-certified founder (Dr. John Diaz, plastic surgeon); 24/7 unlimited messaging and coaching, free shipping
The fine print
- Compounded semaglutide/tirzepatide are not FDA-approved — not the same as Wegovy, Ozempic, or Zepbound
- Published pricing shown is for the compounded line — brand-name pricing isn't itemized
- Prescription isn't guaranteed — a provider reviews eligibility after checkout
Vaylen
The most complete menu in the mid-tier: flat pricing, brand-name access, an oral route, and a LegitScript pharmacy.
Why it's a deal
- LegitScript-certified with all-50-state reach
- Offers compounded, FDA-approved brand-name, and oral routes
- Flat $179 sema / $239 tirz — no teaser step-up
The fine print
- Pricing is mid-pack, not rock-bottom
- You pay for the breadth of options
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Value Score.
Neither one the right fit? Every program that outscores RxSpan MD is ranked on the RxSpan MD alternatives ranking, and the same list for the other side is on alternatives to Vaylen.
More head-to-heads
Prices, states and verification reflect each program's public disclosures at last check; the Value Score is our editorial judgment per the methodology. “Save vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.