Head-to-head · Value Score
CoreAge Rx vs Polly
Two GLP-1 deals, scored on the same six factors. CoreAge Rx lands a Value Score of 93, Polly a 83. Here's what each one really costs past month one — and where each one bites back.
CoreAge Rx
Grade A+ · Excellent
Est. first month
$99/mo
Save ~72% vs brand self-pay
Polly
Grade B+ · Good Value
Est. first month
$179/mo month-to-month
$179/mo month-to-month ($135/mo on a 6-month plan, paid up front)
Save ~49% vs brand self-payThe verdict
CoreAge Rx takes it on Value Score, 93 to 83 — an est. $99/mo first month, with no teaser step-up baked in. Polly isn't out of it: Someone who wants one flat price from the first dose to maintenance, and who will start month to month before deciding whether a prepaid Polly plan is worth it.
CoreAge Rx is a featured partner of this site: one flat, all-in monthly price on both molecules, in all 50 states.
Deal-by-deal
The numbers that decide it. Green ✓ marks the stronger side on each line.
| Deal | CoreAge Rx | Polly |
|---|---|---|
| Value Score | 93 (A+) | 83 (B+) |
| Est. first month | $99/mo | $179/mo month-to-month ($135/mo on a 6-month plan, paid up front) |
| Save vs brand self-pay | ~72% | ~49% |
| Semaglutide | $99/mo | $179/mo month-to-month ($135/mo on a 6-month plan, paid up front) |
| Tirzepatide | $149/mo | $279/mo month-to-month ($199/mo on a 6-month plan, paid up front) |
| Both molecules | Yes | Yes |
| Pricing | Flat — no step-up | Flat — no step-up |
| Coverage | U.S., state limits shown at intake | All 50 states |
Factor by factor
The six factors behind each Value Score. The orange bar marks the stronger side. See the methodology.
CoreAge Rx
CoreAge Rx charges $99 a month for compounded semaglutide and $149 for tirzepatide, with supplies and shipping included, and says that price holds at every dose.
Why it's a deal
- $99 a month for semaglutide and $149 for tirzepatide, and CoreAge Rx's own FAQ states that higher doses cost the same as the starting dose.
- No step-up after month one: CoreAge Rx says the price you lock in at checkout is the price you pay in every later month.
- One figure covers it all. CoreAge Rx lists supplies and free shipping inside the monthly price and charges no membership or platform fee.
- If the doctor does not approve your prescription, CoreAge Rx says it refunds 100% of the checkout charge automatically.
- A U.S. board-certified physician reviews your intake, and CoreAge Rx says you usually hear back within about 24 hours.
- Prescribing is handled by the MD Integrations medical groups, and CoreAge Rx names the physicians, with license numbers, who treat patients in California, Massachusetts, Rhode Island and Vermont.
- CoreAge Rx also sells lower-dose microdosing plans, $149 a month for semaglutide and $199 for tirzepatide, for people who want a smaller weekly dose.
- Refills run through your CoreAge Rx account: the company contacts you before each refill is billed, and you can reorder, cancel, or change your card and address there.
- Orders ship by no-contact delivery, so nobody has to be home to sign for the CoreAge Rx package.
The fine print
- CoreAge Rx charges your card at checkout, before a clinician has looked at your intake. The refund promise covers a declined prescription, but the money leaves first.
- CoreAge Rx does not name its compounding pharmacy on the site. You have to call or email support to find out which pharmacy will fill your order.
- CoreAge Rx is compounded only: no brand-name Wegovy or Zepbound, and compounded semaglutide and tirzepatide are not FDA-approved.
- CoreAge Rx's compounded tirzepatide is usually made with vitamin B12. If you want it without, you have to say so at intake, and the prescriber decides.
- CoreAge Rx takes no insurance and will not send a prescription to your local pharmacy, so it is cash pay through its own pharmacy network.
- All sales are final once CoreAge Rx ships, so cancel in your account before the next refill is billed rather than after the box arrives.
- In some states CoreAge Rx needs a live chat or video visit before a prescription, which adds a step to the 24-hour review.
- CoreAge Rx is not the lowest semaglutide price on this site. A few programs list lower rates; what CoreAge Rx offers is a price that does not change with your dose.
Polly
Polly charges the same price at every dose, $179 a month for semaglutide and $279 for tirzepatide month to month, with two named compounding pharmacies, next-day shipping and no membership fee.
Why it's a deal
- Polly names both of its compounding pharmacies, Hallandale Pharmacy and VialsRx, which most sellers at this price do not
- One price at every dose: Polly says your cost stays the same when your dose goes up, on every plan
- No membership or consultation fee: the Polly price covers the provider visit, the medication, syringes and alcohol pads, and free next-day air shipping
- Polly publishes its whole plan ladder: semaglutide $179 month to month, $166 a month on 3 months and $135 on 6; tirzepatide $279, $216 and $199
- Both compounded semaglutide and tirzepatide, with providers available in all 50 states, and HSA and FSA cards accepted at Polly
The fine print
- Polly's lowest prices need a 6-month plan paid in one charge up front ($1,194 for tirzepatide); month to month costs $44 more for semaglutide and $80 more for tirzepatide
- Polly's 3- and 6-month plans are not refundable after the first month, and ending one early reprices the shipments you received at the month-to-month rate
- Polly's prices sit in its help center rather than on its home page, which lists the treatments without a figure
- Once a Polly order enters provider review or pharmacy processing it cannot be canceled, so turn off auto-refill before the next order starts
- Polly's home page does not carry the plain statement most rivals make, that compounded medication is not FDA-approved
- Compounded injectable only at Polly, with no brand-name or oral option
We earn a commission when you start treatment through some links on this site, at no extra cost to you. It never changes a Value Score.
Neither one the right fit? Every program that outscores CoreAge Rx is ranked on the CoreAge Rx alternatives ranking, and the same list for the other side is on alternatives to Polly.
More head-to-heads
The programs scoring closest to this pair, side by side.
Prices, states and verification reflect each program's public disclosures at last check; the Value Score is our editorial judgment per the methodology. "% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on each provider's site. Not medical advice; see our disclosure.