Head-to-head · Value Score
Sesame Care vs yourEra
Two GLP-1 deals, scored on the same six factors. Sesame Care lands a Value Score of 87, yourEra a 87. Here's what each one really costs past month one — and where each one bites back.
Sesame Care
Grade A- · Great Deal
Est. first month
$149/mo for the drug alone, plus Sesame's membership
$149/mo for the drug alone, plus Sesame's membership ($99 billed every 28 days, or $59/mo only on the 12-month prepay)
yourEra
Grade A- · Great Deal
Est. first month
From $79/mo
From $79/mo (same price at every dose)
Save ~77% vs brand self-payThe verdict
It's a dead heat — Sesame Care and yourEra both land a Value Score of 87. Price it on your own priorities: Sesame Care for shoppers who want genuine fda-approved brand-name glp-1s and the ability to pick their own provider and see the price up front, rather than one fixed compounded program. yourEra for people who want to see a price before handing over any details, and who want both molecules from a program that states one rate at every dose.
Deal-by-deal
The numbers that decide it. Green ✓ marks the stronger side on each line.
| Deal | Sesame Care | yourEra |
|---|---|---|
| Value Score | 87 (A-) | 87 (A-) |
| Est. first month | $149/mo for the drug alone, plus Sesame's membership ($99 billed every 28 days, or $59/mo only on the 12-month prepay) | From $79/mo (same price at every dose) |
| Save vs brand self-pay | — | ~77% |
| Semaglutide | Brand Wegovy pill from $149/mo at 1.5 and 4 mg only, $299/mo at 9 and 25 mg — plus Sesame care: $59/mo only on the 12-month prepay, otherwise $99 billed every 28 days (13 charges a year) | From $79/mo (same price at every dose) |
| Tirzepatide | Brand Zepbound vial $299/mo (2.5 mg), $399 (5 mg), $449 (7.5–15 mg); KwikPen $299 / $399 / $499 / $699 (10–15 mg) — plus Sesame care: $59/mo on the 12-month prepay, otherwise $99 per 28 days | From $159/mo (same price at every dose) |
| Both molecules | Yes | Yes |
| Pricing | Watch | Flat — no step-up |
| Coverage | Nationwide marketplace | All 50 states |
Factor by factor
The six factors behind each Value Score. The orange bar marks the stronger side. See the methodology.
Sesame Care
An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.
What's good
- Real FDA-approved brand-name access — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and Rybelsus
- Established platform (operating since 2018) with LegitScript, BBB accreditation and large third-party review volume
- You choose the provider and see the price up front — genuine marketplace transparency
- Oral routes available (Wegovy pill, Rybelsus)
The fine print
- A generalist marketplace, not a dedicated weight-loss program — lighter ongoing hand-holding than a specialist desk
- Two-part cost (a platform subscription plus the medication) makes the true monthly total harder to compare
- Brand-name cash prices can run high without insurance
yourEra
A publicly priced program with no quiz-wall - semaglutide from $79 and tirzepatide from $159, one price at every dose - sold beside a longevity menu you should read past.
Why it's a deal
- Publishes prices openly on the site - from $79 semaglutide and $159 tirzepatide - while many compounders hide pricing behind an intake quiz
- Both compounded semaglutide and tirzepatide, plus a broader menu (NAD+, microdosing, optional coaching/nutritionist/lab bundle)
- Markets a 50-state licensed-clinician network; no insurance required and HSA/FSA accepted
The fine print
- Both headline figures are "from" rates rather than fixed ones, so the plan you are placed on may cost more than the card says
- Compounded only and not FDA-approved — not equivalent to brand Wegovy/Ozempic/Zepbound, and availability can tighten as brand shortages resolve
- Injectable only - no FDA-approved brand-name lane and no oral option - and the NAD+ and microdosing lines sit on the same menu, so check which product a price belongs to
- Thin independent footprint; the 50-state and efficacy claims are self-reported
We earn a commission when you start treatment through some links on this site, at no extra cost to you. It never changes a Value Score.
Neither one the right fit? Every program that outscores Sesame Care is ranked on the Sesame Care alternatives ranking, and the same list for the other side is on alternatives to yourEra.
More head-to-heads
The programs scoring closest to this pair, side by side.
Prices, states and verification reflect each program's public disclosures at last check; the Value Score is our editorial judgment per the methodology. "% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on each provider's site. Not medical advice; see our disclosure.