Head-to-head · Value Score
CoreAge Rx vs Enhance MD
Two GLP-1 deals, scored on the same six factors. CoreAge Rx lands a Value Score of 93, Enhance MD a 85. Here's who gives you the honest lower price — and where each one bites back.
CoreAge Rx
#1 · Grade A+ · Best Value
Est. first month
$99/mo
Save ~89% vs brand-nameEnhance MD
#9 · Grade A- · Great Deal
Est. first month
$249 every 4 weeks (13 charges a year)
Save ~87% vs brand-nameThe verdict
CoreAge Rx takes it on Value Score, 93 to 85 — an est. $99/mo first month, with no teaser step-up baked in. Enhance MD isn't out of it: Shoppers who want a clearly published tiered price with real provider oversight and lab testing, and don't mind a higher entry price for it.
CoreAge Rx is also our overall #1 pick across the whole deals ranking — a flat, all-in price on both molecules in all 50 states. That's why it wins here on the score, not just this matchup.
Deal-by-deal
The numbers that decide it. Green ✓ marks the stronger side on each line.
| Deal | CoreAge Rx | Enhance MD |
|---|---|---|
| Value Score | 93 (A+) | 85 (A-) |
| Est. first month | $99/mo | $249 every 4 weeks (13 charges a year) |
| Save vs brand-name | ~89% | ~87% |
| Semaglutide | $99/mo | $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay |
| Tirzepatide | $149/mo | $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay |
| Both molecules | Yes | Yes |
| Pricing | Flat — no step-up | Watch |
| Coverage | All 50 states | Not publicly listed |
Factor by factor
The six factors behind each Value Score. The orange bar marks the stronger side. See the methodology.
CoreAge Rx
The honest lowest price: both molecules at one flat, all-in monthly rate that never steps up after month one.
Why it's a deal
- Flat, all-in monthly price with no intro-rate step-ups after month one
- Both compounded semaglutide and tirzepatide on one account
- Available in all 50 states
- Straightforward, low-friction cancellation — no lock-in
The fine print
- Not the rock-bottom sticker — a couple of teaser tiers advertise lower month-one rates
- No FDA-approved brand-name option (compounded only)
- Does not yet publicly name its 503A/B pharmacy partner
Enhance MD
A transparent, dose-flat compounded menu (microdose to sema+tirz combo) with 6-month lab testing and NAD+ on the side — priced higher at entry, with a first-month sema teaser to read past.
Why it's a deal
- Transparent, dose-flat tiered pricing published up front (microdose, sema, tirz, combo)
- Includes 6-month lab testing and provider-led care rather than a bare prescription
- NAD+ and adjacent longevity support available on the same platform
The fine print
- Compounded only — not FDA-approved, and no brand-name or oral/sublingual route
- Semaglutide's $112 first month steps up to $212 — a teaser to plan around
- Higher entry price than the rock-bottom flat-fee programs
- States served are not publicly listed — confirm coverage before you sign up
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Value Score.
Neither one the right fit? Every program that outscores CoreAge Rx is ranked on the CoreAge Rx alternatives ranking, and the same list for the other side is on alternatives to Enhance MD.
More head-to-heads
Prices, states and verification reflect each program's public disclosures at last check; the Value Score is our editorial judgment per the methodology. “Save vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.