Enhance MD review
Value Score82/100
A transparent, dose-flat compounded menu (microdose to sema+tirz combo) with 6-month lab testing and NAD+ on the side — priced higher at entry, with a first-month sema teaser to read past.
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Advertised price
From $249
$249 every 4 weeks (13 charges a year)
How much does Enhance MD cost?
The price Enhance MD publishes is $249 every 4 weeks (13 charges a year). Compounded semaglutide is listed at $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay. Tirzepatide is listed at $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay. We flag this one to watch: confirm the ongoing rate with Enhance MD before you count on it.
- Semaglutide
- $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay
- Tirzepatide
- $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay
- Coverage
- Not publicly listed
- Brand-name
- Compounded only
The Value Score card
Enhance MD scored on our six published factors. See the methodology.
Enhance MD · 82/100
From $249
What's good
- Transparent, dose-flat tiered pricing published up front (microdose, sema, tirz, combo)
- Includes 6-month lab testing and provider-led care rather than a bare prescription
- NAD+ and adjacent longevity support available on the same platform
Read the fine print
- Compounded only — not FDA-approved, and no brand-name or oral/sublingual route
- Semaglutide's $112 first month steps up to $212 — a teaser to plan around
- Higher entry price than the rock-bottom flat-fee programs
- States served are not publicly listed — confirm coverage before you sign up
The bottom line
Best for: Shoppers who want a clearly published tiered price with real provider oversight and lab testing, and don't mind a higher entry price for it.
For comparison, see CoreAge Rx, a featured partner (Value Score 81/100).
Programs to compare
Compare with other deals
The programs scoring closest to Enhance MD, out of 428 others we track.
Shopping Enhance MD against a specific rival? We put it head to head with our featured partner on CoreAge Rx vs Enhance MD, and every program that undercuts or outscores it — starting with Telos Rx, the closest match on score — is ranked on the Enhance MD alternatives ranking.
- $99/mo injectableTelos Rx— Among the lowest published GLP-1 entry prices anywhere — microdosed semaglutide from $49/mo and tirzepatide from $99/mo — on a deep needle-free and oral menu, but the rock-bottom rates require a 6–12 month commitment, so the real month-to-month cost runs higher.83/100
- $79/mo month-to-month on the 1-month planLean Meds— One of the lowest month-to-month rates here — $79 for semaglutide and $109 for tirzepatide, flat at every dose — advertised in a hero that quotes $49, which is the twelve-month tier.83/100
- $149/mo for the drug alone, plus Sesame's membershipSesame Care— An established national telehealth marketplace with the widest real brand-name GLP-1 access in the ranking — Wegovy (pen and pill), Zepbound, Ozempic and Mounjaro — plus provider-by-provider price transparency.82/100
- From $99/moFifty 410— Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers.82/100
- $155/moTuyo Health— Tuyo Health is a US telehealth weight-loss program founded and run by Dr. German Echeverry, a board-certified anesthesiologist, with personalized GLP-1 care and labs included.82/100
- From $180/moVytora Health— Vytora Health is a 50-state-plus-DC telehealth platform offering compounded semaglutide and tirzepatide alongside brand-name Mounjaro and Zepbound, plus NAD+ and sermorelin peptides.82/100
More programs we track (24)
- Kongo84
- MyFastRx84
- NextMeds84
- REMEVi84
- ZYP Medical84
- bmiMD83
- MadeMed83
- Candor Rx83
- Cora Health83
- Polly83
- Tyde Wellness83
- Precision Telemed83
- EdgeRx82
- CoreAge Rx81
- Bodi Envi81
- boostAGErx81
- Curex81
- EverSlim81
- GOAL.MD81
- Good Girl Rx81
- Rivo Health81
- Trillium Meds81
- Alan Meds81
- Renlo Health81
395 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page come from Enhance MD's own website; the Value Score is our editorial judgment per the methodology."% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on Enhance MD's site. Not medical advice; see our disclosure.