Enhance MD review
A transparent, dose-flat compounded menu (microdose to sema+tirz combo) with 6-month lab testing and NAD+ on the side — priced higher at entry, with a first-month sema teaser to read past.
Est. first month
From $249
$249 every 4 weeks (13 charges a year)
How much does Enhance MD cost?
The price Enhance MD publishes is $249 every 4 weeks (13 charges a year). Compounded semaglutide is listed at $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay. Tirzepatide is listed at $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay. We flag this one to watch: confirm the ongoing rate with Enhance MD before you count on it, because a low first month can step up afterward. That works out about 87% under our ~$1,349/mo brand-name cash reference.
- Semaglutide
- $249 every 4 weeks month-to-month (13 charges a year); $212/mo only on the 12-month prepay
- Tirzepatide
- $329 every 4 weeks month-to-month (13 charges a year); $280/mo only on the 12-month prepay
- Coverage
- Not publicly listed
- Brand-name
- Compounded only
The Value Score card
Enhance MD scored on our six published factors. See the methodology.
Why it's a deal
- Transparent, dose-flat tiered pricing published up front (microdose, sema, tirz, combo)
- Includes 6-month lab testing and provider-led care rather than a bare prescription
- NAD+ and adjacent longevity support available on the same platform
Read the fine print
- Compounded only — not FDA-approved, and no brand-name or oral/sublingual route
- Semaglutide's $112 first month steps up to $212 — a teaser to plan around
- Higher entry price than the rock-bottom flat-fee programs
- States served are not publicly listed — confirm coverage before you sign up
The bottom line
Best for: Shoppers who want a clearly published tiered price with real provider oversight and lab testing, and don't mind a higher entry price for it. A transparent, dose-flat compounded menu (microdose to sema+tirz combo) with 6-month lab testing and NAD+ on the side — priced higher at entry, with a first-month sema teaser to read past.
Ranked #9 of 418 programs we track — see our #1 deal, CoreAge Rx, for comparison.
Compare with other deals
The programs scoring closest to Enhance MD, out of 417 others we track.
Shopping Enhance MD against a specific rival? We put it head to head with our top-scoring pick on CoreAge Rx vs Enhance MD, and every program that undercuts or outscores it — starting with bmiMD, the closest match on score — is ranked on the Enhance MD alternatives ranking.
- $119/mo (promotional rate against a $199.80-$228.60 list price)bmiMD— Semaglutide at $119 and tirzepatide at $179, both advertised as discounts against list prices roughly twice as high - and both sitting on a storefront whose cheapest headline number is a peptide, not a GLP-1.86/100
- From $99/moFresh Day Meds— Weekly compounded injections from $99 for semaglutide and $140 for tirzepatide, sold beside four other treatment categories - the prices are visible up front, but they are floors rather than fixed rates.86/100
- $183/mo on the annual plan ($2,196 billed annually)Elara Health and Wellness— Physician-guided care with quarterly labs and a health coach built into the price rather than sold beside it - but every headline figure is an annual-plan rate, and no month-to-month price is published at all.86/100
- $99/mo injectableTelos Rx— Among the lowest published GLP-1 entry prices anywhere — microdosed semaglutide from $49/mo and tirzepatide from $99/mo — on a deep needle-free and oral menu, but the rock-bottom rates require a 6–12 month commitment, so the real month-to-month cost runs higher.85/100
- $129/mo injectableStrut Health— A low, auto-refill entry price on injectable semaglutide, and one of the few places selling the same molecule as a lozenge - though the lozenge is now the dearer of the two routes.85/100
- $239/mo quarterly (from $199/mo on 6 months)MadeMed— Not the cheapest, but the most honest about what a titrated dose actually costs.85/100
More programs we track (24)
- #1 CoreAge Rx93
- #3 Vitara RX91
- #4 Mint Med90
- #2 Trimi Health89
- #5 Sesame Care87
- #6 yourEra87
- #13 NewSelf87
- #7 HealthRX86
- #8 RxSpan MD86
- #17 Ondra Health86
- #21 Belle Health85
- #22 Embody85
- #23 Jyra Health85
- #14 ShedRx84
- #15 Sprout Health84
- #16 Sunlight84
- #24 Big Easy Weight Loss84
- #25 CoraDoc84
- #26 Effecty84
- #27 Kongo84
- #28 MyFastRx84
- #29 NextMeds84
- #30 Piper84
- #31 REMEVi84
387 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page were read from Enhance MD's own website on ; the Value Score is our editorial judgment per the methodology. “% vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on Enhance MD's site. Not medical advice; see our disclosure.