Rx.com review
Names the pharmacy that fills the vial, with a street address, and refuses to auto-renew — behind a banner quoting another drug's prepay rate.
Est. first month
From $175
$175 (semaglutide), month to month
How much does Rx.com cost?
The price Rx.com publishes is $175 (semaglutide), month to month. Compounded semaglutide is listed at $175/mo month-to-month ($146 only on a 6-month prepay). Tirzepatide is listed at $285/mo month-to-month ($259 only on a 6-month prepay). We flag this one to watch: confirm the ongoing rate with Rx.com before you count on it, because a low first month can step up afterward. That works out about 87% under our ~$1,349/mo brand-name cash reference.
- Semaglutide
- $175/mo month-to-month ($146 only on a 6-month prepay)
- Tirzepatide
- $285/mo month-to-month ($259 only on a 6-month prepay)
- Coverage
- 49 states (its own banner says all 50)
- Brand-name
- Compounded only
The Value Score card
Rx.com scored on our six published factors. See the methodology.
Why it's a deal
- "No automatic renewals" is printed under the plan card itself rather than buried in terms
- Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
- One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included
- A provider who declines to prescribe does not charge you for medication
Read the fine print
- The advertised $146 is a six-month prepay on the other molecule
- Its plan page says 49 states served while its own banner says all 50
- Injection only — no oral route and no brand-name lane
- LegitScript is claimed in the footer and we did not verify who holds the id
The bottom line
Best for: Someone who will read the plan card rather than the banner, and who values no auto-renewal over the lowest sticker. Names the pharmacy that fills the vial, with a street address, and refuses to auto-renew — behind a banner quoting another drug's prepay rate.
Ranked #181 of 427 programs we track — see our #1 deal, CoreAge Rx, for comparison.
Compare with other deals
The programs scoring closest to Rx.com, out of 426 others we track.
Shopping Rx.com against a specific rival? We put it head to head with our top-scoring pick on CoreAge Rx vs Rx.com, and every program that undercuts or outscores it — starting with TOM Weight Loss, the closest match on score — is ranked on the Rx.com alternatives ranking.
- From $199/mo (all doses, compounded)TOM Weight Loss— TOM Weight Loss is a two-state clinic run by a triple board-certified physician, charging $199 a month for compounded semaglutide at any dose up to 2.4 mg a week, with tirzepatide from $249.73/100
- $225/moTru2u— Tru2u is a US direct-to-consumer telehealth and wellness store offering provider-guided compounded GLP-1 weight-loss therapy alongside hair, skincare, and supplement lines.73/100
- From $170/mo (compounded)YourHealthRx— YourHealthRx is a scientist-founded peptide and GLP-1 telehealth platform available in all 50 states and DC via a multi-state (IMLC) clinician network.73/100
- From $149/mo (starting dose, compounded)altRX— altRX is a dual-modality telehealth platform offering compounded GLP-1s plus all four brand-name FDA-approved options — Mounjaro, Ozempic, Wegovy, and Zepbound.72/100
- From $196/mo (starting dose, compounded)Clinic Secret— Clinic Secret (clinicsecret.com), launched late 2025, is a functioning US GLP-1 telehealth platform offering compounded semaglutide and tirzepatide for weight loss, plus a pentadeca arginate peptide.72/100
- From $149/mo (quarterly plan, compounded)Coivas— Coivas is an all-inclusive GLP-1 telehealth service operated by WellVi LLC (d/b/a Coivas) with prescriptions through Arora Health & Aesthetics, LLC.72/100
More programs we track (24)
- #128 Care Bare Rx73
- #129 Fridays73
- #168 Arc-173
- #169 Citizen Meds73
- #170 Injectco73
- #171 Kin Meds73
- #172 Livv73
- #173 LumiMeds73
- #174 Measured73
- #175 NuvaHealth73
- #176 PauseRX73
- #177 Somi Health73
- #185 Contour Health72
- #186 ElitePhysiqMD72
- #187 Healthicare72
- #188 HeliMeds72
- #189 Lavender Sky Health72
- #190 LevelsRx72
- #191 MediRX72
- #192 Mevo Health72
- #193 NativeMed72
- #194 NexLife72
- #195 NuBloom72
- #196 OrderlyMeds72
396 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page were read from Rx.com's own website on ; the Value Score is our editorial judgment per the methodology. “% vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on Rx.com's site. Not medical advice; see our disclosure.