Signos review
Value Score67/100
Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app.
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Advertised price
From $199/mo
From $199/mo (starting dose, compounded)
How much does Signos cost?
The price Signos publishes is From $199/mo (starting dose, compounded). We flag this one to watch: confirm the ongoing rate with Signos before you count on it.
- Semaglutide
- From $199/mo (6-month plan, compounded)
- Tirzepatide
- From $199/mo (starting dose, compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
The Value Score card
Signos scored on our six published factors. See the methodology.
What's good
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
Read the fine print
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
The bottom line
Best for: Shoppers who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
For comparison, see CoreAge Rx, a featured partner (Value Score 81/100).
Programs to compare
Compare with other deals
The programs scoring closest to Signos, out of 428 others we track.
Shopping Signos against a specific rival? We put it head to head with our featured partner on CoreAge Rx vs Signos, and every program that undercuts or outscores it — starting with MyStart Health, the closest match on score — is ranked on the Signos alternatives ranking.
- From $299/moMyStart Health— MyStart Health offers all-inclusive compounded semaglutide and tirzepatide at $299/month with a price-lock guarantee, same-day physician consultations, and 24/7 care team access.67/100
- From $249/moNuDay Rx— NuDay Rx is a GLP-1 weight-loss telehealth service (on the CareValidate/careGLP platform) that pairs medication with video coaching and lifestyle support.67/100
- From $119/moPomegranate Health— Pomegranate Health sells compounded semaglutide from $119 and tirzepatide from $149 on Starter plans, with no membership requirement and prices published on its app subdomain rather than its marketing site.67/100
- From $149/moSilhouette MD— Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.67/100
- From $225/moWisp— Wisp is a US telehealth provider whose weight care vertical offers brand-name Wegovy, Zepbound, and Saxenda alongside a compounded sublingual semaglutide drops formulation at $225/month.67/100
- From $127/moWoodwork— Woodwork is a men's health telehealth platform built by Grindr that offers compounded GLP-1 weight-loss medications alongside ED care, with a focus on serving gay and queer men.67/100
More programs we track (24)
- Roen Rx68
- RxPepsDirect68
- Ryze Rx68
- Nex Gen Health Rx68
- VevaRX68
- Edessa68
- ARSYNL Rx67
- Aurelius Health Group67
- Corsica Health67
- DreamHug Medical67
- FeelGood67
- HealthOn67
- Synergy Rx67
- The Edit67
- Luvo Health66
- Alloy66
- Ascend Vitality66
- BeyondMD66
- EOS Health66
- HelloWellness66
- Joi + Blokes66
- LevelUp Rx66
- LIV by WellNow66
- Luma Meds66
395 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page come from Signos' own website; the Value Score is our editorial judgment per the methodology."% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on Signos' site. Not medical advice; see our disclosure.