RxPepsDirect review
RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform offering semaglutide/B12 from $25/vial and tirzepatide/B12 from $45/vial, dispensed through Optimal Balance Pharmacy.
Est. first month
From $79/mo
From $79/mo (starting dose, visit fee and shipping included, compounded)
How much does RxPepsDirect cost?
The price RxPepsDirect publishes is From $79/mo (starting dose, visit fee and shipping included, compounded). Tirzepatide is listed at From $99/mo (starting dose, visit fee and shipping included, compounded). We flag this one to watch: confirm the ongoing rate with RxPepsDirect before you count on it, because a low first month can step up afterward. That works out about 94% under our ~$1,349/mo brand-name cash reference.
- Semaglutide
- From $79/mo (starting dose, visit fee and shipping included, compounded)
- Tirzepatide
- From $99/mo (starting dose, visit fee and shipping included, compounded)
- Coverage
- 28 states
- Brand-name
- Compounded only
The Value Score card
RxPepsDirect scored on our six published factors. See the methodology.
Why it's a deal
- Industry-lowest GLP-1 pricing: compounded semaglutide from $25/vial, tirzepatide from $45/vial — no subscription or recurring commitment required
- Real 503A telehealth Rx: licensed NP/PA prescribers + MD medical director (Dr. Jonathan Snipes, NPI 1821250077); patient-specific Rx dispensed by
- FedEx overnight shipping at $15 flat; ships pre-reconstituted and includes syringes, alcohol wipes, and reusable cooled travel case
- Independent batch COA testing by Eagle Analytical (FDA-registered, A2LA ISO 17025): 54/54 sterility and endotoxin passes published publicly on
- No subscription required; $39 flat visit fee covers up to 3 peptides per Rx; pay per vial with no ongoing commitment
Read the fine print
- The medication is sold per milligram rather than per month, so the bill rises with every titration — the quoted figures are a starting protocol only, and no price is published for the dose you end up on
- The $39 medical visit fee is charged on every order, not once, and $15 flat shipping is added to each order as well
- The dosing behind the quoted price is twice-weekly at 0.15 mg semaglutide, below the 0.25 mg weekly labeled starting dose — a microdose protocol, not the labeled schedule
- Not available in California, and 28 states in total
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
The bottom line
Best for: Shoppers who want lowest per-vial GLP-1 cost: compounded sema $25, tirz $45, $39 telehealth Rx, no subscription, 28 states. RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform offering semaglutide/B12 from $25/vial and tirzepatide/B12 from $45/vial, dispensed through Optimal Balance Pharmacy.
Ranked #280 of 427 programs we track — see our #1 deal, CoreAge Rx, for comparison.
Compare with other deals
The programs scoring closest to RxPepsDirect, out of 426 others we track.
Shopping RxPepsDirect against a specific rival? We put it head to head with our top-scoring pick on CoreAge Rx vs RxPepsDirect, and every program that undercuts or outscores it — starting with Premium Health, the closest match on score — is ranked on the RxPepsDirect alternatives ranking.
- From $275/mo (all doses, compounded)Premium Health— Premium Health (premiumhealth.us) is a LegitScript-certified telehealth provider offering compounded GLP-1 medications for weight loss via an all-inclusive membership.68/100
- From $199/mo (starting dose, compounded)Regenics— Regenics is a hybrid in-office and telemedicine health-optimization clinic based in Tarzana, CA, pairing compounded GLP-1 weight loss with TRT.68/100
- From $216/mo (plus a separate fee, compounded)Roen Rx— Roen Rx is a multi-service telehealth platform offering compounded semaglutide alongside brand-name Ozempic, Wegovy, Zepbound and Mounjaro with insurance coordination, across all 50 states and DC.68/100
- From $199/mo (starting dose, 3 month plan, compounded)Ryze Rx— Ryze Rx is a prescription telehealth platform for weight loss, TRT and peptide therapy, prescribing through board-certified physicians and shipping from US-licensed compounding pharmacies.68/100
- $190 per 30-day supply, month-to-month (the $99 on its homepage is the 360-day prepay rate, $1,188 up front)Nex Gen Health Rx— Compounded semaglutide at $190 and tirzepatide at $239 per thirty-day supply, advertised as $99 and $149 a month — figures that are the 360-day prepay rates, $1,188 and $1,788 charged in one go.68/100
- $189/mo month-to-month (or $399 on a three-month prepay; its own page also prints $167 a month and a $467 total)VevaRX— A thirty-six-state program selling semaglutide at $189 a month on a page that also prints $167, $399 and $467 for the same drug — and tirzepatide only as a three-month prepay whose advertised per-month equivalent does not divide.68/100
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396 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page were read from RxPepsDirect's own website on ; the Value Score is our editorial judgment per the methodology. “% vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on RxPepsDirect's site. Not medical advice; see our disclosure.