Cost Plus Drugs review
Mark Cuban's transparent-pricing online pharmacy.
Est. first month
From $279/mo
From $279/mo (brand Ozempic)
How much does Cost Plus Drugs cost?
The price Cost Plus Drugs publishes is From $279/mo (brand Ozempic). We flag this one to watch: confirm the ongoing rate with Cost Plus Drugs before you count on it, because a low first month can step up afterward.
- Semaglutide
- From $279/mo (brand Ozempic)
- Tirzepatide
- Not disclosed
- Coverage
- All 50 states
- Brand-name
- Yes
The Value Score card
Cost Plus Drugs scored on our six published factors. See the methodology.
Why it's a deal
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Read the fine print
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
The bottom line
Best for: Shoppers who want the cheapest transparent-pricing brand-name Ozempic channel. Mark Cuban's transparent-pricing online pharmacy.
Ranked #326 of 427 programs we track — see our #1 deal, CoreAge Rx, for comparison.
Compare with other deals
The programs scoring closest to Cost Plus Drugs, out of 426 others we track.
Shopping Cost Plus Drugs against a specific rival? We put it head to head with our top-scoring pick on CoreAge Rx vs Cost Plus Drugs, and every program that undercuts or outscores it — starting with Spry, the closest match on score — is ranked on the Cost Plus Drugs alternatives ranking.
- From $199/mo (starting dose, compounded)Spry— Spry is a weight-loss and anti-aging telehealth platform pairing compounded semaglutide ($199/mo) and tirzepatide ($299/mo) with three longevity peptides — BPC-157, NAD+, and sermorelin ($249–$299/mo).65/100
- From $159/mo (2.5 mg dose, plus a separate fee, compounded)Vita Bella— Vita Bella is a Nevada-based telehealth membership platform (Vita Bella Health, LLC) that offers compounded GLP-1 weight-loss medications alongside hormone therapy.65/100
- $299/mo month-to-month (the $179 headline is the first month only, after an automatic welcome coupon)MEDGm— Compounded semaglutide at $299 a month and tirzepatide at $399, sold behind a "starting at $179" headline that is a first-month coupon — on a site whose own questions promise the price never increases.64/100
- From $175/mo (starting dose, compounded)Genesis Health— Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound.64/100
- From $199/mo (compounded)Heros Health— Heros Health is a direct-to-consumer telehealth platform offering compounded semaglutide and tirzepatide for weight loss on a flat program price — $149 the first month.64/100
- From $266/mo (starting dose, compounded)Lean Rx— Lean Rx is a Sacramento-based telehealth technology platform offering compounded semaglutide from $266 and tirzepatide from $399, in injectable, sublingual and tablet form.64/100
More programs we track (24)
- #310 Lyfe Rx66
- #311 TeleCareSpot66
- #312 Vitalex Health66
- #313 WePeptideRx66
- #315 AVARA Rx65
- #316 Avono Health65
- #317 Boston Medical Group65
- #318 Fitstry65
- #319 Harmony Wellness Clinic65
- #320 LunaRx65
- #321 OnlyRx65
- #322 Society of You65
- #330 Levers Health64
- #331 Metaboost Rx64
- #332 Onyx Weight Loss64
- #333 Open Water Rx64
- #334 Roboclinic64
- #335 RxSaludable64
- #336 TeleHealth Weight Solutions64
- #337 Whoosh Wellness64
- #314 MyDrHank63
- #339 Elara MD63
- #340 Eve63
- #341 Fierce Health63
396 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page were read from Cost Plus Drugs's own website on ; the Value Score is our editorial judgment per the methodology. “% vs brand-name” compares the lowest disclosed monthly price against a ~$1,349/mo brand-name cash reference. Prices change — confirm on Cost Plus Drugs's site. Not medical advice; see our disclosure.