Cost Plus Drugs review
Value Score64/100
Mark Cuban's transparent-pricing online pharmacy.
We earn a commission when you start treatment through some links on this site, at no extra cost to you. CoreAge Rx is a featured partner, and providers we work with may appear first. It never changes the Value Score.
Advertised price
From $279/mo
From $279/mo (brand Ozempic)
How much does Cost Plus Drugs cost?
The price Cost Plus Drugs publishes is From $279/mo (brand Ozempic). We flag this one to watch: confirm the ongoing rate with Cost Plus Drugs before you count on it.
- Semaglutide
- From $279/mo (brand Ozempic)
- Tirzepatide
- Not disclosed
- Coverage
- All 50 states
- Brand-name
- Yes
The Value Score card
Cost Plus Drugs scored on our six published factors. See the methodology.
What's good
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
Read the fine print
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
The bottom line
Best for: Shoppers who want the cheapest transparent-pricing brand-name Ozempic channel.
For comparison, see CoreAge Rx, a featured partner (Value Score 81/100).
Programs to compare
Compare with other deals
The programs scoring closest to Cost Plus Drugs, out of 428 others we track.
Shopping Cost Plus Drugs against a specific rival? We put it head to head with our featured partner on CoreAge Rx vs Cost Plus Drugs, and every program that undercuts or outscores it — starting with Spry, the closest match on score — is ranked on the Cost Plus Drugs alternatives ranking.
- From $199/moSpry— Spry is a weight-loss and anti-aging telehealth platform pairing compounded semaglutide ($199/mo) and tirzepatide ($299/mo) with three longevity peptides — BPC-157, NAD+, and sermorelin ($249–$299/mo).65/100
- From $159/moVita Bella— Vita Bella is a Nevada-based telehealth membership platform (Vita Bella Health, LLC) that offers compounded GLP-1 weight-loss medications alongside hormone therapy.65/100
- $299/mo month-to-monthMEDGm— Compounded semaglutide at $299 a month and tirzepatide at $399, sold behind a "starting at $179" headline that is a first-month coupon — on a site whose own questions promise the price never increases.64/100
- From $175/moGenesis Health— Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound.64/100
- From $199/moHeros Health— Heros Health is a direct-to-consumer telehealth platform offering compounded semaglutide and tirzepatide for weight loss on a flat program price — $149 the first month.64/100
- From $266/moLean Rx— Lean Rx is a Sacramento-based telehealth technology platform offering compounded semaglutide from $266 and tirzepatide from $399, in injectable, sublingual and tablet form.64/100
More programs we track (24)
- Vitalex Health66
- WePeptideRx66
- Fridays65
- AVARA Rx65
- Avono Health65
- Boston Medical Group65
- Fitstry65
- Harmony Wellness Clinic65
- LunaRx65
- Metaboost Rx65
- OnlyRx65
- Society of You65
- Levers Health64
- Onyx Weight Loss64
- Open Water Rx64
- Roboclinic64
- RxSaludable64
- Whoosh Wellness64
- MyDrHank63
- Elara MD63
- Eve63
- Fierce Health63
- Freya Meds63
- Livea63
395 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page come from Cost Plus Drugs' own website; the Value Score is our editorial judgment per the methodology."% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on Cost Plus Drugs' site. Not medical advice; see our disclosure.