Onyx Weight Loss review
Value Score64/100
Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.
We earn a commission when you start treatment through some links on this site, at no extra cost to you. CoreAge Rx is a featured partner, and providers we work with may appear first. It never changes the Value Score.
Advertised price
From $228/mo
From $228/mo (starting dose, compounded)
How much does Onyx Weight Loss cost?
The price Onyx Weight Loss publishes is From $228/mo (starting dose, compounded). Tirzepatide is listed at From $280/mo (starting dose, compounded). We flag this one to watch: confirm the ongoing rate with Onyx Weight Loss before you count on it.
- Semaglutide
- From $228/mo (starting dose, compounded)
- Tirzepatide
- From $280/mo (starting dose, compounded)
- Coverage
- 8 states
- Brand-name
- Compounded only
The Value Score card
Onyx Weight Loss scored on our six published factors. See the methodology.
What's good
- Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
- Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
- Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
- Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
- Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team
Read the fine print
- Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
- No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
- Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
- Labs not included or mentioned; no baseline bloodwork protocol published
- Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
The bottom line
Best for: Shoppers who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.
For comparison, see CoreAge Rx, a featured partner (Value Score 81/100).
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Compare with other deals
The programs scoring closest to Onyx Weight Loss, out of 428 others we track.
Shopping Onyx Weight Loss against a specific rival? We put it head to head with our featured partner on CoreAge Rx vs Onyx Weight Loss, and every program that undercuts or outscores it — starting with Heros Health, the closest match on score — is ranked on the Onyx Weight Loss alternatives ranking.
- From $199/moHeros Health— Heros Health is a direct-to-consumer telehealth platform offering compounded semaglutide and tirzepatide for weight loss on a flat program price — $149 the first month.64/100
- From $266/moLean Rx— Lean Rx is a Sacramento-based telehealth technology platform offering compounded semaglutide from $266 and tirzepatide from $399, in injectable, sublingual and tablet form.64/100
- From $247/moLevers Health— Levers Health sells compounded semaglutide from $247 and tirzepatide from $296 on dose-capped plans, plus a separate low-dose and microdose GLP-1 line aimed at longevity rather than weight loss.64/100
- $169/moOpen Water Rx— Open Water Rx is a clinician-guided telehealth service covering all 50 states, publishing compounded semaglutide at $169, tirzepatide at $219 and a daily oral semaglutide tablet at $199 a month.64/100
- From $179/moRoboclinic— Roboclinic is an AI-first telehealth platform, operated by BrickFi, Inc., that starts you with an AI health assistant and then routes you to a board-certified provider for GLP-1 weight-loss care.64/100
- From $179/moRxSaludable— RxSaludable is a Spanish-language GLP-1 weight-loss telehealth service (atencion en espanol) offering compounded semaglutide from $99 the first month ($179/mo after).64/100
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395 more are reviewed too — see every GLP-1 program we track, ranked.
Pricing and coverage on this page come from Onyx Weight Loss' own website; the Value Score is our editorial judgment per the methodology."% vs brand-name self-pay" compares a program's lowest disclosed monthly price against $349/mo, Wegovy's self-pay price at NovoCare Pharmacy, every standard dose after the two-month intro offer (checked October 2026). Prices change — confirm on Onyx Weight Loss' site. Not medical advice; see our disclosure.